
by
John Bach
photo/Lisa
Ventre
"The
medical profession has a responsibility not only for the cure of the sick
and for the prevention of disease but for the advancement of knowledge
upon which both depend."
Dr. Robert McCance, 1950
Dr. Albert Sabin
shared his colleague's approach to research when he developed the oral
polio vaccine while on faculty at UC's College of Medicine and staff of
Children's Hospital. His dogged pursuit of discovery virtually wiped out
the disease that once crippled and killed millions of children worldwide.
Sabin's legacy at the College of Medicine today is as real as Sabin Way,
the road on which many UC scientists travel to get to their labs.
Walking in Sabin's footsteps, both literally and figuratively, is Dr.
Jeff Whitsett, a UC faculty member and researcher at Children's. Whitsett,
an icon in pulmonary medicine and neonatology, recently discovered a gene
linked to a rare lung disease in adults and infants. He first gained international
attention, however, when he helped develop a drug called Survanta, which
lubricates premature infants' lungs, keeping them from sticking together
and collapsing. Survanta, often the difference between life and death
for preemies, has been used to treat nearly a half million infants since
its approval by the Food and Drug Administration in 1991.
Jim Feuer, Ed '78, knows intimately the value of Whitsett's work. When
Feuer's 8-year-old son Benjamin was born, his lungs had not fully developed.
Though twin brother Aaron went home after a week, Ben was placed on a
ventilator and kept in the intensive care unit the first five weeks of
his life.
"He was working too hard to breathe," Feuer recalled of his
5-pound, 8-ounce child. "The doctors tried other drugs, but he didn't
do well. The next day they put him on Survanta. We don't know that he
would not have lived without it, but it really speeded up his lung maturity
and enabled him to get off the ventilator."
As public relations director at Children's, Feuer has had the rare opportunity
to meet the scientist behind the life-giving science. "It is really
neat to be able to go up to Dr. Whitsett and thank him for the work he
has done," Feuer says. "Ben has been incredibly healthy ever
since. His lungs are fine."
The methods of discovery have evolved enormously since Sabin peered into
his microscope here four decades ago and even since Whitsett broke through.
But the desire to unravel nature's secrets to help people like Benjamin
remains. Today's researchers are simply getting a closer look at the human
body.
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